Please join us for Biomedical Data Science Grand Rounds with David Tabb, PhD, Professor of Molecular Biology and Human Genetics at Stellenbosch University on Thursday, April 29 at 12:00 p.m. via Zoom!
Talk title: "Proteogenomics for Tuberculosis and for Non-Model Organisms”
Location: Zoom (no registration required)
Webinar URL:
https://dartmouth.zoom.us/j/92900128442?pwd=aTdUdi9qSkJHeUlNM0R3YjliRWtiUT09
Webinar ID: 929 0012 8442
Passcode: 013564
Host: Kwame Wiredu, Burroughs Wellcome Fund Fellow and Candidate for PhD in QBS
Talk Summary
Genome and transcriptome sequencing has become ubiquitous, but our methods for leveraging sequencing data in proteomics have frequently lagged behind. This talk will discuss two routes for this incorporation: 1) microbial genome sequencing to detect Mycobacterium tuberculosis strain-specific expression, and 2) RNA-Seq assembly to enable non-model organism proteomics in Salvia hispanica. This talk will strive to explain proteogenomics for researchers who may only have heard the term in the past.
Biography
David Tabb joined the field of proteomics in 1996, when he began his PhD in Molecular Biotechnology in the John Yates Laboratory at the University of Washington. Since 2001, he has been publishing in the area of proteome informatics, seeking ways to maximize the information we produce from LC-MS/MS. Dr. Tabb joined the faculty of the Department of Biomedical Informatics at Vanderbilt University in 2005, and became an Associate Professor in 2011. In 2015, Dr. Tabb moved to Stellenbosch University in South Africa to re-center his career in training tuberculosis researchers, and he began a new research emphasis in non-model organisms. At the start of 2021, he moved to the Institut Pasteur to develop new skills in top-down proteomics.
