~~Please join us for Medicine Grand Rounds: ~~THE JOSEPH P. LYNCH, III, MD, LECTURE

~~Alix Ashare, MD, PhD

Associate Professor of Medicine and of Microbiology/Immunology

~~8:00 a.m. – 9:00 a.m.
Auditorium E, Rubin Building, Dartmouth-Hitchcock Medical Center

Co-sponsored by the Section of Pulmonary and Critical Care Medicine and the Department of Medicine
The Geisel School of Medicine at Dartmouth

~~Dr. Ali Ashare obtained her MD from Vanderbilt University and her PhD from the University of Iowa.  After completing a residency in Internal Medicine and a Pulmonary Fellowship at the University of Iowa, she moved her clinical and research program to the Geisel School of Medicine at Dartmouth where she is currently an Associate Professor of Medicine and Microbiology & Immunology.  Her research focuses on the role of lung macrophages in the development of regional inflammation in the CF lung.  Currently her laboratory is investigating the potential mechanisms of regional heterogeneity of lung inflammation in patients with inflammatory lung diseases, with an emphasis on the investigation of regional differences in alveolar macrophage function in these patient populations. At Dartmouth-Hitchcock Medical Center, she is a physician-scientist in Pulmonary and Critical Care Medicine.  In addition, she is the Director of both the Therapeutics Development Center for CF and the Translational Research Core at Dartmouth and facilitates collaborative clinical and translational research studies.

Objectives – Participants will be able to:
1. Describe the complexity of CFTR mutations and the importance of personalized medicine in patients with cystic fibrosis
2. Discuss the role of inflammation in the development of CF lung disease and how targeted therapies may impact inflammation